Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Furin Substrate, Fluorogenic
A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor II, JSH-23
The NF-κB Activation Inhibitor II, JSH-23, also referenced under CAS 749886-87-1, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ mTOR Inhibitor XI, Torin1
mTOR Inhibitor XI, Torin1, CAS 1222998-36-8, is a cell-permeable, highly potent, ATP-competitive inhibitor of mTOR and DNA-PK (IC50 = 4.32 and 6.34 nM, respectively).
MilliporeSigma™ Calbiochem™ (--)-Nicotine, Ditartrate
Potent agonist of the nicotinic acetylcholine receptor.
MilliporeSigma™ Calbiochem™ P2Y Antagonist II, BPTU
A phenoxypyridinyl-phenylurea that acts as a highly selective P2Y1 antagonist (Ki = 6nM against 0.5nM 2-MeS-ADP for hu
MilliporeSigma™ Calbiochem™ Aphidicolin
Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase.
MilliporeSigma™ Calbiochem™ Cyclo(Arg-Gly-Asp-D-Phe-Val)
Potent inhibitor of cell adhesion.
MilliporeSigma™ Calbiochem™ AhR Agonist V, VAF347
The AhR Agonist V, VAF347 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ InSolution™ Nocodazole
Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture.
MilliporeSigma™ Calbiochem™ Notch Transcription Factor Inhibitor, SAHM1
Notch Transcription Factor Inhibitor, SAHM1, is a cell-permeable inhibitor that prevents assembly in the NOTCH1 trans-activation complex.
MilliporeSigma™ Calbiochem™ Benztropine
An antagonist of muscarinic M1 and M3 receptors that induces robust differentiation of oligodendrocytes precursor cell differentiation (EC50 = 500nM) and promotes myelination.
MilliporeSigma™ Calbiochem™ Tetrabenazine, TBZ
A monoamine-depleting agent that blocks vesicular monoamine transporter 2 activity. Promotes late-stage differentiation of Pdx1 + pancreatic progenitor cells into Ngn3 + endocrine precursors.
MilliporeSigma™ Calbiochem™ Antipain, Dihydrochloride
Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes.
MilliporeSigma™ Calbiochem™ Apoptosis Activator III, Embelin
The Apoptosis Activator III, Embelin, also referenced under CAS 550-24-3, controls the biological activity of Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.